One such formulation (Aller-7/NR-A2) is used to treat allergic rhinitis. The formulation contains seven plants including piper nigrum. The formula was tested on Balb/c mice, Swiss Albino mice, Wistar Albino rats (WAR) with paw edema as well as on WARs with Freund's adjuvant-induced arthritis. The test showed that the formula has an anti-inflammatory effect.
Another formula, Aller-7, is a novel, botanical formulation developed also for the treatment of allergic rhinitis. It uses seven medicinal plant extracts, including those form Piper nigrum, Zingiber officinale and Piper longum. Tested on guinea pigs, the formula showed antihistaminic and antispasmodic effects.
(Source: HerbMed, http://www.herbmed.org)
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